This paper presents the findings of a study that had examined the relationship between 30% reservation scheme by procuring entities and special groups’ participation in public tendering opportunities in Tanzania that is moderated by the role of confidence and perception. Primary data were collected in Tanzania Mainland, involving 550 special groups and 16 procuring entities, using a survey instrument. Results indicate that preferential procurement scheme is positively and significantly explained by confidence and perception, e-procurement system usability, implementation of preferential procurement by PE, special groups involvement in public tendering opportunities and technical readiness. This study provides implications on how preference and reservation scheme can help to ensure that women, elders, youth and persons with disabilities are engaged in awarding tenders in public procurement. Consequently, the participation of special groups will be improved, and hence reduces the extent of poverty and improve human well being in society at large. Thus, the study emphasizes the deliberate efforts in creating more friendly environments to special groups so as to boost their participation as means towards reaching vision 2050 which insisits on inclusivity of each group in the economy.